反应详情

Compound 7 was prepared using the synthetic route for Compound 6 using 4-methylbenzaldehyde in procedure 5. Purification was accomplished using column chromatography to provide the title compound as a solid (mp 210-214° C.). 1H-NMR (CDCl3) δ 8.1 (m, 2H); 7.5 (m, 3H); 7.3-7.2 (m, 5H); 7.1 (s, 4H); 6.2(s, 1H), 5.4 (s, 1H); 2.3 (s,3H). 13C-NMR (CDCl3) δ 170.9; 165.6; 156.5; 141.4; 138.2; 136.6; 132.1; 132.0; 129.4; 129.32; 129.29; 129.0; 128.5; 127.9; 126.9; 112.5; 58.4; 20.9. Mass spec (MH+ 353). Analysis for C24H20N2O; calculated, C 81.79, H 5.72, N 7.95; found C 81.43, H 5.91, N 7.75.

1. customCompound 7 was prepared
2. customPurification