反应详情

1H-Imidazol-4-yl(4-methoxy[1,1′-biphenyl]-3-yl)methanol (0.94 g) was dissolved in dichloromethane (100 ml) and manganese dioxide (5.52 g) was added. The mixture was stirred at room temperature for 14 h, filtrated and concentrated. To the obtained residue was added ethyl acetate and the mixture was crystallized to give the title compound (0.84 g) as a colorless solid.

1. filtrationfiltrated
2. concentrationconcentrated
3. additionTo the obtained residue was added ethyl acetate
4. customthe mixture was crystallized