HRID1059170

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1ccco1

HCID4393688

2-(Tributylstannyl)furan

C16H30OSn

结构：CC(C)C(O)(c1cccc(Br)c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID18668522

未命名化合物

PRODUCTS

生成物

结构：CC(C)C(O)(c1cccc(-c2ccco2)c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID18668591

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

催化剂HCID178418397

未命名化合物

PROCEDURE

实验过程

By the reaction in the same manner as in Example 28-(i) using 1-(3-bromophenyl)-1-(1-trityl-1H-imidazol-4-yl)-2-methyl-1-propanol (1.70 g), tri-n-butyl(2-furyl)tin (1.29 ml) and tetrakis(triphenylphosphine)palladium((0) (110 mg), the title compound (1.62 g) was obtained as colorless powder crystals.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-26be396d70844c3a94decd4477ec331f
来源数据集: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06518257B1
来源说明: uspto-grants-2003_02

反应 SMILES

Br[C:2]1[CH:3]=[C:4]([C:8]([C:13]2[N:14]=[CH:15][N:16]([C:18]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:17]=2)([OH:12])[CH:9]([CH3:11])[CH3:10])[CH:5]=[CH:6][CH:7]=1.C([Sn](CCCC)(CCCC)[C:42]1[O:43][CH:44]=[CH:45][CH:46]=1)CCC>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[O:43]1[CH:44]=[CH:45][CH:46]=[C:42]1[C:2]1[CH:3]=[C:4]([C:8]([C:13]2[N:14]=[CH:15][N:16]([C:18]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH:17]=2)([OH:12])[CH:9]([CH3:10])[CH3:11])[CH:5]=[CH:6][CH:7]=1