HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → N-{4'-[1-hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl][1,1'-biphenyl]-4-yl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | N-{4'-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl][1,1'-biphenyl]-4-yl}acetamide | HCID 18668637 | — |
| Product | N-{4'-[1-hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl][1,1'-biphenyl]-4-yl}acetamide | HCID 178474083 | 20.6% |
Reaction Steps
By the reaction in the same manner as in Example 4-(iii) using N-{4′-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl][1,1′-biphenyl]-4-yl}acetamide (601 mg) and pyridine hydrochloride (0.17 g), the title compound (73 mg) was obtained as colorless powder crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-3b6594682e4d4828a316516710db993e |
| Source note | uspto-grants-2003_02 |