Pyridinium chloride → HCID 178485314, compound

HRID 1059198Notes

Reaction equation

HRID 1059198 reaction equation
[OH:1][C:2]([C:30]1[CH:31]=[C:32]([C:36]2[CH:41]=[CH:40][CH:39]=[C:38]([C:42]([NH:44][CH3:45])=[O:43])[CH:37]=2)[CH:33]=[CH:34][CH:35]=1)([C:6]1[N:7]=[CH:8][N:9](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:10]=1)[CH:3]([CH3:5])[CH3:4].Cl.N1C=CC=CC=1>>[OH:1][C:2]([C:30]1[CH:31]=[C:32]([C:36]2[CH:41]=[CH:40][CH:39]=[C:38]([C:42]([NH:44][CH3:45])=[O:43])[CH:37]=2)[CH:33]=[CH:34][CH:35]=1)([C:6]1[N:7]=[CH:8][NH:9][CH:10]=1)[CH:3]([CH3:5])[CH3:4]

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 18668594HCID 18668594, compound

Product 1

HCID 178485314HCID 178485314, compoundYield 16.2%

Procedure

By the reaction in the same manner as in Example 4-(iii) using 3′-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl[1,1′-biphenyl]-3-carboxamide (576 mg) and pyridine hydrochloride (0.22 g), the title compound (55 mg) was obtained as colorless powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example

Sources & evidence

ORD record
ord-7569ad77bac34a6e844e35ceb4205913
Source dataset
uspto-grants-2003_02
Patent number
US06518257B1

Reaction notes

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