HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-bromo-N-ethylbenzamide → HCID 18668657, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-bromo-N-ethylbenzamide | HCID 4160271 | — |
| Reactant | 4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenylboronic acid | HCID 18668578 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 18668657 | HCID 18668657 | 43.8% |
Reaction Steps
By the reaction in the same manner as in Example 33-(ii) using 4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenylboronic acid (7.40 g, 14.7 mmol), 3-bromo-N-ethylbenzamide (2.20 g) and tetrakis(triphenylphosphine)palladium(0) (0.441 g), the title compound (2.56 g) was obtained as a yellow amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-804c03ec61254a5a883cc2cd01fba1b6 |
| Source note | uspto-grants-2003_02 |