HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178485317, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4'-[1-hydroxy-(1-trityl-1H-imidazol-4-yl)ethyl]-N-methyl[1,1'-biphenyl]-3-carboxamide | HCID 69531931 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | HCID 178485317 | HCID 178485317 | 47.9% |
Reaction Steps
By the reaction in the same manner as in Example 41-(ii) using [4′-[1-hydroxy-(1-trityl-1H-imidazol-4-yl)ethyl]-N-methyl[1,1′-biphenyl]-3-carboxamide (527 mg), 10% palladium carbon (527 mg) and 1N hydrochloric acid (0.935 ml), the title compound (144 mg) was obtained as colorless powder crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-319f46fec8ab4db1b148e8c0fb17f152 |
| Source note | uspto-grants-2003_02 |