Pyridinium chloride → HCID 178450132, compound

HRID 1059231Notes

Reaction equation

HRID 1059231 reaction equation
[CH3:1][CH:2]([CH3:41])[C:3]([C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([C:35]2[CH:36]=[N:37][CH:38]=[CH:39][CH:40]=2)[CH:30]=1)([C:5]1[N:6]=[CH:7][N:8](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:9]=1)[OH:4].Cl.N1C=CC=CC=1>>[NH:8]1[CH:9]=[C:5]([C:3]([C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([C:35]3[CH:36]=[N:37][CH:38]=[CH:39][CH:40]=3)[CH:30]=2)([OH:4])[CH:2]([CH3:41])[CH3:1])[N:6]=[CH:7]1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 18668632HCID 18668632, compound

Product 1

HCID 178450132HCID 178450132, compoundYield 92.3%

Procedure

By the reaction in the same manner as in Example 4-(iii) using 2-methyl-1-[3-(3-pyridyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (0.57 g) and pyridine hydrochloride (208 mg), the title compound (288 mg) was obtained as colorless powder crystals.

Workup

  1. customBy the reaction in the same manner as in Example

Sources & evidence

ORD record
ord-2a405f05339f4598b03db7e99ba93e4d
Source dataset
uspto-grants-2003_02
Patent number
US06518257B1

Reaction notes

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