HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 6-bromo-N-isopropylpicolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 6-Bromopyridine-2-carboxylic acid | HCID 593919 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Product | 6-bromo-N-isopropylpicolinamide | HCID 18668624 | — |
Reaction Steps
By the reaction in the same manner as in Example 55-(i) using 6-bromopicolinic acid (3.04 g), isopropylamine (5 ml), 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride (3.44 g) and 1-hydroxybenzotriazole (2.70 g), the title compound (3.10 g) was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-469fb88597ea4934b2d7ea73f8b3f4bd |
| Source note | uspto-grants-2003_02 |