HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenylboronic acid → HCID 18668635, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenylboronic acid | HCID 18668578 | — |
| Reactant | 6-bromo-N-isopropylpicolinamide | HCID 18668624 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 18668635 | HCID 18668635 | 57.9% |
Reaction Steps
By the reaction in the same manner as in Example 33-(ii) using 4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenylboronic acid (3.10 g), 6-bromo-N-isopropyl-2-pyridinecarboxamide (1.13 g) and tetrakis(triphenylphosphine)palladium(0) (0.160 g), the title compound (1.67 g) was obtained as a colorless amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-acf8c8e990e44ac5913336993105baec |
| Source note | uspto-grants-2003_02 |