Methanol → HCID 23565313, compound

Participants

Reaction Steps

To a solution of 1.78 g of 9-(1,3-dithian-2-ylidenemethyl)-1,3,5-trimethyl-3-azabicyclo[3.3.1]nonane in a solvent mixture of methanol (27 ml) with water (3 ml) was added 3.53 g of mercuric chloride under stirring and the resulting mixture was then refluxed for 20 hours. Next, the reaction mixture was poured into ethyl acetate/an aqueous solution of potassium carbonate and filtered through celite. After. distilling off the solvent under reduced pressure, the residue was purified by silica gel column chromatography (eluted with n-hexane/ethyl acetate) to thereby give 0.23 g of the title compound as a colorless oily substance.

Provenance & Evidence