反应详情

To a solution of 33 g of 4-chloro-o-anisic acid in sulfuric acid (100 ml) was added 20 g of potassium nitrate under ice-cooling and the resulting mixture was stirred for 2 hours. The reaction mixture was added to ice/water and extracted with ethyl acetate and the organic layer was dried over anhydrous magnesium sulfate. After distilling off the solvent under reduced pressure, 41 g of the title compound was obtained as pale yellow crystals.

1. temperaturecooling
2. extractionextracted with ethyl acetate
3. dry with materialthe organic layer was dried over anhydrous magnesium sulfate
4. distillationAfter distilling off the solvent under reduced pressure