HCID 18670385, compound → HCID 18670243, compound

Participants

Reaction Steps

To a solution of 1.17 g of 7-methoxy-10-(methoxymethyl)-10H-pyrazino[2,3-b][1,4]-benzoxazine-8-methanol in 50 ml of 1,2-dichloroethane was added 3.2 g of manganese dioxide and the resulting mixture was heated under reflux for 2 hours. The reaction mixture was filtered through celite. After distilling off the solvent under reduced pressure, 0.75 g of the title compound was obtained as a brown solid.

Provenance & Evidence