Benzeneacetic acid, 4-hydroxy-, methyl ester → HCID 18670277, compound

HRID 1059332Notes

Reaction equation

HRID 1059332 reaction equation
[CH2:1]([O:8][C:9]([N:11]1[CH2:16][CH2:15][CH:14]([OH:17])[CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O[C:19]1[CH:24]=[CH:23][C:22]([CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:21][CH:20]=1>>[CH2:1]([O:8][C:9]([N:11]1[CH2:16][CH2:15][CH:14]([O:17][C:19]2[CH:24]=[CH:23][C:22]([CH2:25][C:26]([O:28][CH3:29])=[O:27])=[CH:21][CH:20]=2)[CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 518900Benzeneacetic acid, 4-hydroxy-, methyl esterHCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Product 1

HCID 18670277HCID 18670277, compound

Procedure

1-(Benzyloxycarbonyl)piperidin-4-ol and methyl 4-hydroxyphenylacetate were treated in the same manner as the one of Production Example 65 to thereby give the title compound as a pale green powder.

Sources & evidence

ORD record
ord-529ff43e10e643da947dd3860106e062
Source dataset
uspto-grants-2003_02
Patent number
US06518423B1

Reaction notes

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