trans-1,4-Dibromo-2-butene → HCID 18670107, compound
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]1[C:16]([Cl:17])=[N:15][CH:14]=[CH:13][N:12]=1)([O-:3])=[O:2].[Br:18][CH2:19]/[CH:20]=[CH:21]/[CH2:22]Br>>[Br:18][CH2:19]/[CH:20]=[CH:21]/[CH2:22][N:10]([C:11]1[C:16]([Cl:17])=[N:15][CH:14]=[CH:13][N:12]=1)[C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2]Participants
3
Procedure
Similar to Production Example 132, 5.04 g of 2-[(2-nitrophenyl)amino]-3-chloropyrazine was treated with (E)-1,4-dibromo-2-butene to thereby give 0.34 g of the title compound.
Sources & evidence
- ORD record
- ord-8b2b9a5ec8c64658a0941aaaa26e2a71
- Source dataset
- uspto-grants-2003_02
- Patent number
- US06518423B1
Reaction notes
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