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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1059383Generated: November 3, 2026

2-Benzyl-5-nitropyridine → 6-Benzylpyridin-3-amine

https://huagongshe.com/reaction/1059383

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Benzyl-5-nitropyridineHCID 18670221—
CatalystHCID 178418390HCID 178418390—
SolventEthyl AcetateHCID 8857—
Product6-Benzylpyridin-3-amineHCID 1162970999.5%

Reaction Steps

389 mg of 2-benzyl-5-nitropyridine was dissolved in ethyl acetate and 153 mg of 10% palladium carbon was added thereto. Then the resulting mixture was stirred under a hydrogen gas stream at room temperature under atmospheric pressure for 30 minutes. Then the reaction mixture was filtered through celite. After distilling off the solvent under reduced pressure, 333 mg of the title compound was obtained as an amber oily substance.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06518423B1
Source datasetuspto-grants-2003_02
ORD IDord-3d90a3f3768d4c6cad00aa16c8f3f118
Source noteuspto-grants-2003_02