Imidazole → HCID 18670375, compound

HRID 1059402Notes

Reaction equation

HRID 1059402 reaction equation
CS(O[CH2:6][CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]2[S:17][C:16]3[N:18]=[CH:19][CH:20]=[N:21][C:15]=3[N:14](COC)[C:13]=2[CH:25]=1)(=O)=O.[NH:26]1[CH:30]=[CH:29][N:28]=[CH:27]1>>[N:26]1([CH2:6][CH2:7][CH2:8][C:9]2[CH:10]=[CH:11][C:12]3[S:17][C:16]4[N:18]=[CH:19][CH:20]=[N:21][C:15]=4[NH:14][C:13]=3[CH:25]=2)[CH:30]=[CH:29][N:28]=[CH:27]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 18670196HCID 18670196, compound

Product 1

HCID 18670375HCID 18670375, compound

Procedure

Similar to Example 1094, 3-[10-methoxymethyl-10H-pyrazino[2,3-b][1,4]benzothiazin-8-yl]propyl methanesulfonate was reacted with imidazole and then treated by the same method as the one of Example 434 to thereby give the following compound.

Workup

  1. additiontreated by the same method as the one of Example 434
  2. customto thereby give the following compound

Sources & evidence

ORD record
ord-f5bf6014073d4405888d5f318090d6c8
Source dataset
uspto-grants-2003_02
Patent number
US06518423B1

Reaction notes

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