Methyl chloroformate → HCID 23564738, compound

HRID 1059459Notes

Reaction equation

HRID 1059459 reaction equation
[O:1]([CH2:9][C:10]1[CH:11]=[CH:12][C:13]2[S:18][C:17]3[N:19]=[CH:20][CH:21]=[N:22][C:16]=3[NH:15][C:14]=2[CH:23]=1)[Si:2]([C:5]([CH3:8])([CH3:7])[CH3:6])([CH3:4])[CH3:3].[C:24](Cl)(=[O:27])[O:25][CH3:26]>>[CH3:26][O:25][C:24]([N:15]1[C:14]2[CH:23]=[C:10]([CH2:9][O:1][Si:2]([C:5]([CH3:6])([CH3:7])[CH3:8])([CH3:4])[CH3:3])[CH:11]=[CH:12][C:13]=2[S:18][C:17]2[N:19]=[CH:20][CH:21]=[N:22][C:16]1=2)=[O:27]

Participants

3

Reactant 2

HCID 6586Methyl chloroformateHCID 23564737HCID 23564737, compound

Product 1

HCID 23564738HCID 23564738, compound

Procedure

4.0 g of 8-(tert-butyldimethylsiloxymethyl)-10H-pyrazino[2,3-b][1,4]benzothiazine was subjected to the procedure described in Example 1570 but using methyl chlorocarbonate instead of acetyl chloride to thereby give 2.5 g of the title compound as a yellow oily substance.

Sources & evidence

ORD record
ord-e68333a321ce40dab3fbd4738a1a0de7
Source dataset
uspto-grants-2003_02
Patent number
US06518423B1

Reaction notes

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