HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromoaniline → N-(3-cyanophenyl)-N'-(4-bromophenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromoaniline | HCID 7807 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 3-Isocyanatobenzonitrile | HCID 2733315 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | N-(3-cyanophenyl)-N'-(4-bromophenyl)urea | HCID 18630693 | 80.5% |
Reaction Steps
A mixture of 3-cyanophenyl isocyanate (3.76 g, 26.1 mmol) and 4-bromoaniline (4.5 g, 26.1 mmol) in 1:1 tetrahydrofuran:chloroform (100 mL). After 72 h at ambient temperature, product was isolated by filtration, the filtrate was washed with cold chloroform and air dried to give 6.6 g of N-(3-cyanophenyl)-N′-(4-bromophenyl)urea (21 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521614B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-8181b82618894f04998a9cbf8dcd1e4c |
| Source note | uspto-grants-2003_02 |