Ethanol → 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH2:14])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[CH3:33][O:34][CH2:35][CH2:36][O:37][CH3:38].[CH3:39][CH2:40][OH:41].[Cl:15][c:16]1[cH:17][cH:18][c:19]([B:22]([OH:23])[OH:24])[cH:20][cH:21]1.[K+:30].[K+:31].[K+:32].[OH2:42].[P:25]([O-:26])([O-:27])([O-:28])=[O:29]>>[c:2]1(-[c:19]2[cH:18][cH:17][c:16]([Cl:15])[cH:21][cH:20]2)[cH:3][c:4]([NH2:14])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]Participants
8
Sources & evidence
- ORD record
- ord-f2795b804d814512aeabb4a18f505b18
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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