HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(3-amino-2,2-dimethylpropyl)carbamate → N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-2,2-dimethyl-1,3-propylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(3-amino-2,2-dimethylpropyl)carbamate | HCID 4114359 | — |
| Reactant | Isoquinoline-5-sulfonyl chloride hydrochloride | HCID 13116932 | — |
| Product | N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-2,2-dimethyl-1,3-propylenediamine | HCID 21979795 | 97.8% |
Reaction Steps
According to Reference Example 5, Step B, a reaction was performed by using isoquinoline-5-sulfonyl chloride hydrochloride (7.8 g) and Intermediate 56 (5.97 g) to obtain the title compound (11.36 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094789B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-39fe4c2e1195477eb249df5a4f124b5a |
| Source note | uspto-grants-2006_08 |