HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 9951913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 22344731 | HCID 22344731 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 9951913 | HCID 9951913 | — |
Reaction Steps
A solution of Example 52A (00 mg) in methanol:THF (1 mL: 1 mL) was treated with 10% palladium on carbon, stirred under hydrogen (1 atm) for 4 hours, filtered through diatomaceous earth (Celite®), and concentrated. The concentrate was purified by flash column chromatography on silica gel with 2% methanol/dichloromethane to provide 31 mg of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521658B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-abb4691fba6a4e0684a4aff75c33ce09 |
| Source note | uspto-grants-2003_02 |