Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Pyridine, 2-methyl-4-nitro-, 1-oxide | HCID 95291 | — |
| Product | HCID 54513511 | HCID 54513511 | — |
Reaction Steps
To a suspension of sodium hydride (60% dispersion in mineral oil, 1.06 g) in 2-propanol (30 ml) was added 2-methyl-4-nitropyridine N-oxide (3.08 g), and the mixture was stirred at 60° C. for 1 hour. The residue was evaporated under reduced pressure and purified by column chromatography (silica gel 75 g, 5% methanol in dichloromethane) to give 4-isopropyloxy-2-methylpyridine N-oxide (0.78 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06521643B1 |
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| Source dataset | uspto-grants-2003_02 |
|---|
| ORD ID | ord-751898010d0b45978c5b6886e8d83f10 |
|---|
| Source note | uspto-grants-2003_02 |
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