HCID 611601, compound → HCID 18667606, compound

HRID 1059908Notes

Reaction equation

HRID 1059908 reaction equation
[CH3:1][C:2]1[C:3]([C:8]2[CH:9]=[C:10]([N+:14]([O-])=O)[CH:11]=[CH:12][CH:13]=2)=[N:4][CH:5]=[CH:6][CH:7]=1>C(O)C.[Pd]>[CH3:1][C:2]1[C:3]([C:8]2[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=2)[NH2:14])=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 611601HCID 611601, compound

Product 1

HCID 18667606HCID 18667606, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A suspension of 3-(3-methylpyridin-2-yl)nitrobenzene (214 mg) in ethanol (5 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 50 mg) under a hydrogen atmosphere for 2 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(3-methylpyridin-2-yl)aniline (184 mg).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

Sources & evidence

ORD record
ord-68bfaf09080c4978a01f325f3915a425
Source dataset
uspto-grants-2003_02
Patent number
US06521643B1

Reaction notes

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