HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methylpyridin-2-yl)nitrobenzene → 2-(3-Aminophenyl)-4-methylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methylpyridin-2-yl)nitrobenzene | HCID 12811122 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(3-Aminophenyl)-4-methylpyridine | HCID 18667616 | 98.8% |
Reaction Steps
A suspension of 3-(4-methylpyridin-2-yl)nitrobenzene (100 mg) in ethanol (2 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 10 mg) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(4-methylpyridin-2-yl)aniline (85 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521643B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-208ecb5c84814deb92796c10a9b41c0a |
| Source note | uspto-grants-2003_02 |