HCID 18667565, compound → HCID 18667551, compound

HRID 1059941Notes

Reaction equation

HRID 1059941 reaction equation
[C:1]([C:3]1[C:4]([C:9]2[CH:10]=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=2)=[N:5][CH:6]=[CH:7][CH:8]=1)#[N:2]>C(O)C.[Pd]>[C:1]([C:3]1[C:4]([C:9]2[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=2)[NH2:15])=[N:5][CH:6]=[CH:7][CH:8]=1)#[N:2]

Participants

4

Reactant 1

HCID 18667565HCID 18667565, compound

Product 1

HCID 18667551HCID 18667551, compoundYield 145.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A suspension of 3-(3-cyanopyridin-2-yl)nitrobenzene (0.27 g) in ethanol (5 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 80 mg) under a hydrogen atmosphere for 5 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(3-cyanopyridin-2-yl)aniline (0.34 g).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

Sources & evidence

ORD record
ord-1d888504c2c34dca9048abe9b823a947
Source dataset
uspto-grants-2003_02
Patent number
US06521643B1

Reaction notes

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