Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-Nitrophenol | HCID 11137 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Fluoro-4-methylpyridine | HCID 2737403 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18630979 | HCID 18630979 | 40.7% |
Reaction Steps
A suspension of 2-fluoro-4-methylpyridine (1.11 g), 3-nitrophenol (1.67 g) and potassium carbonate (1.80 g) in N,N-dimethylformamide (10 ml) was stirred at 130° C. for 24 hours. After cooling, the mixture was poured into water and stirred for 30 minutes. The precipitate was collected by filtration and dried to give 3-(4-methylpyridin-2-yloxy)-nitrobenzene (935 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06521643B1 |
|---|
| Source dataset | uspto-grants-2003_02 |
|---|
| ORD ID | ord-1a81727cfe404caca37e99d9914bf289 |
|---|
| Source note | uspto-grants-2003_02 |
|---|
