HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18630987, compound → HCID 18630998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18630987 | HCID 18630987 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18630998 | HCID 18630998 | 99.6% |
Reaction Steps
A suspension of 2-(4-methoxypyridin-2-yl)-4-nitrotoluene (293 mg) in tetrahydrofuran (3 ml) and ethanol (3 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 0.1 g) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(4-methoxypyridin-2-yl)-4-methylaniline (256 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521643B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-4c4bda77deef4377b5b650d8a59a8e36 |
| Source note | uspto-grants-2003_02 |