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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1059960Generated: November 2, 2026

HCID 18630987, compound → HCID 18630998, compound

https://huagongshe.com/reaction/1059960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18630987HCID 18630987—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18630998HCID 1863099899.6%

Reaction Steps

A suspension of 2-(4-methoxypyridin-2-yl)-4-nitrotoluene (293 mg) in tetrahydrofuran (3 ml) and ethanol (3 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 0.1 g) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(4-methoxypyridin-2-yl)-4-methylaniline (256 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06521643B1
Source datasetuspto-grants-2003_02
ORD IDord-4c4bda77deef4377b5b650d8a59a8e36
Source noteuspto-grants-2003_02