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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1059978Generated: October 26, 2026

4-(4-Methylpyridin-2-yl)-2-nitrotoluene → HCID 18667479, compound

https://huagongshe.com/reaction/1059978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methylpyridin-2-yl)-2-nitrotolueneHCID 18667647—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 18667479HCID 18667479100%

Reaction Steps

A suspension of 4-(4-methylpyridin-2-yl)-2-nitrotoluene (342 mg) in ethanol (7 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 103 mg) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 2-methyl-5-(4-methylpyridin-2-yl)aniline (297 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06521643B1
Source datasetuspto-grants-2003_02
ORD IDord-7ea27a07174443f89c4307443460703e
Source noteuspto-grants-2003_02