HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18667517, compound → HCID 18667622, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18667517 | HCID 18667517 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18667622 | HCID 18667622 | 100.1% |
Reaction Steps
A suspension of 2-fluoro-5-(4-methoxypyridin-2-yl)nitrobenzene (0.2 g) in ethanol (4 ml) and tetrahydrofuran (3 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 60 mg) under a hydrogen atmosphere for 5 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 2-fluoro-5-(4-methoxypyridin-2-yl)aniline (176 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521643B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-bdf20f9a096d4f1c9ee0aa684a5e9ce7 |
| Source note | uspto-grants-2003_02 |