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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1060089Generated: October 30, 2026

Diethylamine → N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide

https://huagongshe.com/reaction/1060089

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
Reactant2,5-Bis(trifluoromethyl)benzoyl chlorideHCID 2737812—
ProductN,N-Diethyl-2,5-bis(trifluoromethyl)benzamideHCID 15832108—

Reaction Steps

N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide was prepared from 2,5-bis(trifluoromethyl)benzoyl chloride and diethylamine according to General Method E1. The desired intermediate was isolated in quantitative yield (11.3 g) without additional purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06521603B2
Source datasetuspto-grants-2003_02
ORD IDord-c163eb5241c64ddeb62a168da83fc62f
Source noteuspto-grants-2003_02