Ethylamine → 2-tert-butyl-N-ethylbenzamide

HRID 1060173Notes

Reaction equation

HRID 1060173 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7](Cl)=[O:8])([CH3:4])([CH3:3])[CH3:2].[CH2:14]([NH2:16])[CH3:15]>O>[C:1]([C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([NH:16][CH2:14][CH3:15])=[O:8])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 137671862-tert-Butylbenzoyl chloride

Product 1

HCID 186300432-tert-butyl-N-ethylbenzamide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-tert-butyl-N-ethylbenzamide was prepared from 2-tert-butylbenzoyl chloride, prepared in Example 186, and 70% ethylamine in water according to the method of step b of Example 248.

Sources & evidence

ORD record
ord-ba66ff1f735e418c8540bfdd141ab54f
Source dataset
uspto-grants-2003_02
Patent number
US06521603B2

Reaction notes

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