HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → N-Ethyl-1-methyl-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 1-Methyl-1H-pyrazole-4-carboxylic acid | HCID 643160 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-Ethyl-1-methyl-1H-pyrazole-4-carboxamide | HCID 19474722 | 54.7% |
Reaction Steps
N-Ethyl-1-methyl-1H-pyrazole-4-carboxamide was prepared from 1-methyl-1H-pyrazole-4-carboxylic acid and 70% ethylamine in water using the methods of steps a and b of Example 248. The product was purified by flash chromatography with 10% ethyl acetate-hexane and recovered as a white solid in 54.7% yield. m.p. 103-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521603B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-06ba1e1e4291470b81c868fae339bb7e |
| Source note | uspto-grants-2003_02 |