4-Fluorobenzoyl chloride → HCID 22283284, compound

HRID 1060272Notes

Reaction equation

HRID 1060272 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[C:10]([C:11]([OH:13])=[O:12])=[CH:9][CH:8]=[C:7]([O:14][CH3:15])[C:5]=2[N:6]=1.[F:16][C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]([NH:1][C:2]2[S:3][C:4]3[C:10]([C:11]([OH:13])=[O:12])=[CH:9][CH:8]=[C:7]([O:14][CH3:15])[C:5]=3[N:6]=2)=[O:22])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 22283089HCID 22283089, compound

Product 1

HCID 22283284HCID 22283284, compound

Procedure

Using 2-amino-4-methoxy-benzothiazole-7-carboxylic acid methyll ester and 4-fluoro-benzoyl chloride the title compound was obtained as a white solid (91% yield), MS: m/e=361.1 (M+H+).

Sources & evidence

ORD record
ord-0241703bf3db44da83c35bf6d2d55251
Source dataset
uspto-grants-2003_02
Patent number
US06521754B2

Reaction notes

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