HCID 22283409, compound → HCID 22283382, compound

Participants

Reaction Steps

100 mg of 4-fluoro-N-(4-methoxy-7-vinyl-benzothiazol-2-yl)-benzamide (0.3 mmol) were dissolved in methanol (100 ml) and Pd/C (4 mg) were added. The reaction mixture was hydrogenated for 2 hrs. After filtering and evaporation of the solvent the crude product was subjected to column chromatography (silica gel, eluent MeOH/CH2Cl2 1:9). The title compound was obtained in form of white crystals (79 %); F.p.: 165-167° C.

Provenance & Evidence