HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-[(5-isoquinolyl)sulfonyl]-1,3-xylylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-1,3-xylylenediamine | HCID 69525002 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[(5-isoquinolyl)sulfonyl]-1,3-xylylenediamine | HCID 69524243 | 81% |
Reaction Steps
According to Reference Example 5, Step C, a reaction was performed by using Intermediate 63 (5 g) and 10% hydrogen chloride in methanol (20 ml) to obtain the title compound (3.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094789B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-45adba3b20e14f428e038d8658406cee |
| Source note | uspto-grants-2006_08 |