Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → 4-Fluoro-N-(4-isopropoxy-7-piperidin-1-yl-benzothiazol-2-yl)-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide | HCID 10200214 | — |
| 반응물 | 4-Bromo-1-isopropoxy-2-nitrobenzene | HCID 22283241 | — |
| 생성물 | 4-Fluoro-N-(4-isopropoxy-7-piperidin-1-yl-benzothiazol-2-yl)-benzamide | HCID 22283383 | — |
반응 단계
The title compound was prepared strarting from 4-bromo-1-isopropoxy-2-nitro-benzene and piperidine as described for 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide (Example 275) and obtained as a light brown solid in 10 % overall yield, MS: m/e=414 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06521754B2 |
| 출처 데이터셋 | uspto-grants-2003_02 |
| ORD ID | ord-9c01828bcb974277bfc709d7cbcbfaef |
| 출처 메모 | uspto-grants-2003_02 |