HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Bromo-2-nitroanisole → 4-Fluoro-N-(4-methoxy-7-[1,4]oxazepan-4-yl-benzothiazol-2-yl)-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Bromo-2-nitroanisole | HCID 118533 | — |
| Edukt | 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide | HCID 10200214 | — |
| Edukt | 1,4-Oxazepane | HCID 21873275 | — |
| Produkt | 4-Fluoro-N-(4-methoxy-7-[1,4]oxazepan-4-yl-benzothiazol-2-yl)-benzamide | HCID 22283130 | — |
Reaktionsschritte
The title compound was prepared strarting from 4-bromo-1-methoxy-2-nitro-benzene and [1.4]Oxazepane as described for 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide (Example 275) and obtained as a light yellow solid in about 10% overall yield, MS: m/e=402 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06521754B2 |
| Quelldatensatz | uspto-grants-2003_02 |
| ORD ID | ord-43d5f67a7d7a440b9eb342f37c40bad7 |
| Quellennotiz | uspto-grants-2003_02 |