HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(2-Methoxy-5-morpholinophenyl)thiourea | HCID 22015733 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine | HCID 11402861 | — |
Reaction Steps
(2-Methoxy-5-morpholin-4-yl-phenyl)-thiourea (5.0 g, 19 mmol) in chloroform (130 ml) are treated with bromine (960 □1) and the mixture refluxed for 18 hours. After removal of the volatile components in vacuo, the product is recrystallized from THF (2.8 g, 57%). MS: m/e=266 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521754B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-9de9ddc680fb4a49a171b927198dcbc6 |
| Source note | uspto-grants-2003_02 |