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HRID1060407

反应详情

EQUATION

反应方程式

HRID 1060407 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)Nc1ccccc1B(O)O
HCID2773226

{2-[(tert-Butoxycarbonyl)amino]phenyl}boronic acid

C11H16BNO4

结构：COC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)c1c(Cl)cccc1Cl
HCID54284267

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](Cc1ccc(-c2ccccc2NC(=O)OC(C)(C)C)cc1)NC(=O)c1c(Cl)cccc1Cl
HCID54237195

未命名化合物

收率 73.5%

PROCEDURE

实验过程

2-(tert-Butoxycarbonylamino)benzeneboronic acid (0.3 g) was coupled with N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester (270 mg) by a similar procedure as described in Examples 15 to give 250 mg of N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester. ESMS: m/z 543 (MH+).