HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-2-methoxymethoxybenzeneboronic acid → N-(2,6-dichlorobenzoyl)-4-(6-methoxy-2-methoxymethoxyphenyl)-L-phenylalanine ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-2-methoxymethoxybenzeneboronic acid | HCID 22571652 | — |
| Reactant | HCID 54080286 | HCID 54080286 | — |
| Product | N-(2,6-dichlorobenzoyl)-4-(6-methoxy-2-methoxymethoxyphenyl)-L-phenylalanine ethyl ester | HCID 54508489 | — |
Reaction Steps
6-Methoxy-2-methoxymethoxybenzeneboronic acid (1.92 g) was coupled with N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine ethyl ester in a similar procedure as described in Example 5-3) to afford N-(2,6-dichlorobenzoyl)-4-(6-methoxy-2-methoxymethoxyphenyl)-L-phenylalanine ethyl ester (0.942 mg). ESMS m/Z 532 (MH+), 530 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521666B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-9129cea3fc374110a8ddc4161c3f3915 |
| Source note | uspto-grants-2003_02 |