HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,3R,4S,5S)-4-(benzoyloxy)-2-(6-chloro-2-iodo-9H-purin-9-yl)-5-[(ethylamino)carbonyl]tetrahydro-3-furanyl benzoate → (2R,3R,4S,5S)-4-(Benzoyloxy)-5-[(ethylamino)carbonyl]-2-{6-[(9H-fluoren-9-ylmethyl)amino]-2-iodo-9H-purin-9-yl}tetrahydro-3-furanyl benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,3R,4S,5S)-4-(benzoyloxy)-2-(6-chloro-2-iodo-9H-purin-9-yl)-5-[(ethylamino)carbonyl]tetrahydro-3-furanyl benzoate | HCID 10189909 | — |
| Reactant | (9H-Fluoren-9-yl)methanamine | HCID 14555239 | — |
| Product | (2R,3R,4S,5S)-4-(Benzoyloxy)-5-[(ethylamino)carbonyl]-2-{6-[(9H-fluoren-9-ylmethyl)amino]-2-iodo-9H-purin-9-yl}tetrahydro-3-furanyl benzoate | HCID 10190982 | — |
Reaction Steps
Prepared from ((2R,3R,4S,5S)-4-(benzoyloxy)-2-(6-chloro-2-iodo-9H-purin-9-yi)-5-[(ethylamino)carbonyl]-tetrahydro-3-furanyl benzoate (Preparation 19) and 9H-fluoren-9-ylmethylamine by the same method as Preparation 20. The title compound was obtained as a yellow foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525032B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-35bf66fcda4846739a47da7021905cca |
| Source note | uspto-grants-2003_02 |