HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 11562468, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3-bromo-6-methoxyisobenzofuran-1(3H)-one | HCID 12298540 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 11562468 | HCID 11562468 | 91.5% |
Reaction Steps
Triphenyphosphine (42 g, 0.16 moles) was added to 3-bromo-6-methoxy-3H-isobenzofuran-1-one (41 g, 0.169 moles), obtained as described in example 9, suspended in anhydrous acetonitrile (205 ml) under N2. The mixture was heated under reflux and after 3 hours cooled and concentrated to give a solid which was treated with ethyl ether, filtered and concentrated under vacuum. There were thus obtained 74 g of the title compound (yield: 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525055B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-c50dbbda56e043fcb8835cc65a707b03 |
| Source note | uspto-grants-2003_02 |