Dimethylsulphamoyl chloride → 4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N,N-dimethylpiperidine-1-sulfonamide

HRID 1060692Notes

Reaction equation

HRID 1060692 reaction equation
[CH3:1][N:2]([CH3:7])[S:3](Cl)(=[O:5])=[O:4].[CH2:8]([O:10][CH2:11][C:12]1[N:13]([CH2:24][CH2:25][CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[C:14]2[C:19]([CH3:20])=[C:18]([CH3:21])[N:17]=[C:16]([NH2:22])[C:15]=2[N:23]=1)[CH3:9]>>[NH2:22][C:16]1[C:15]2[N:23]=[C:12]([CH2:11][O:10][CH2:8][CH3:9])[N:13]([CH2:24][CH2:25][CH:26]3[CH2:27][CH2:28][N:29]([S:3]([N:2]([CH3:7])[CH3:1])(=[O:5])=[O:4])[CH2:30][CH2:31]3)[C:14]=2[C:19]([CH3:20])=[C:18]([CH3:21])[N:17]=1

Participants

3

Reactant 2

HCID 83372Dimethylsulphamoyl chlorideHCID 129729622-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine

Product 1

HCID 224991534-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N,N-dimethylpiperidine-1-sulfonamide

Procedure

Using the method of Examples 49-56, dimethylsulfamoyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 439.2510.

Sources & evidence

ORD record
ord-8b43fe5e119d40f19f562315f329b9ad
Source dataset
uspto-grants-2003_02
Patent number
US06525064B1

Reaction notes

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