Dimethylsulphamoyl chloride → N'-[4-(4-amino-2-ethoxymethyl-7-methyl-1H-imidazo[4,5-c]pyridin-1-yl)butyl]-N,N-dimethylsulfamide

HRID 1060701Notes

Reaction equation

HRID 1060701 reaction equation
[CH3:1][N:2]([CH3:7])[S:3](Cl)(=[O:5])=[O:4].[CH2:8]([O:10][CH2:11][C:12]1[NH:13][C:14]2[C:19]([CH3:20])=[CH:18][N:17]=[C:16]([NH2:21])[C:15]=2[N:22]=1)[CH3:9]>>[NH2:21][C:16]1[C:15]2[N:22]=[C:12]([CH2:11][O:10][CH2:8][CH3:9])[N:13]([CH2:19][CH2:14][CH2:15][CH2:16][NH:17][S:3]([N:2]([CH3:7])[CH3:1])(=[O:5])=[O:4])[C:14]=2[C:19]([CH3:20])=[CH:18][N:17]=1

Participants

3

Reactant 2

HCID 83372Dimethylsulphamoyl chlorideHCID 178467655HCID 178467655, compound

Product 1

HCID 22499152N'-[4-(4-amino-2-ethoxymethyl-7-methyl-1H-imidazo[4,5-c]pyridin-1-yl)butyl]-N,N-dimethylsulfamide

Procedure

Using the method of Examples 115-135, dimethylsulfamoyl chloride was reacted 4-aminobutyl)-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-4-amine to the desired product. The observed accurate mass was 385.2029.

Sources & evidence

ORD record
ord-959d23dcf71444d9b5b9e148fb5cf783
Source dataset
uspto-grants-2003_02
Patent number
US06525064B1

Reaction notes

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