Sodium Iodide → HCID 18629483, compound

Participants

Reaction Steps

A solution of chloromethyl N-(3-(N-tert-butoxycarbonylamino)-propyl)carbamate (2 g) and sodium iodide (4.5 g) in acetonitrile (15 ml) was stirred for 1 hour at room temperature, evaporated in vacuo, redissolved in dichloromethane and filtered. The filtrate was evaporated in vacuo and the residue was purified by chromatography on silica gel with ethyl acetate/hexane (1:2) as eluent to yield the title compound as colourless crystals.

Provenance & Evidence