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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1060812Generated: October 25, 2026

tert-Butyl 4-oxopiperidine-1-carboxylate → 4-(3,4-Dichloro-benzenesulfonyl)-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1060812

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant4-(3,4-Dichloro-benzenesulfonyl)-piperidineHCID 22397499—
Product4-(3,4-Dichloro-benzenesulfonyl)-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl esterHCID 69434475—

Reaction Steps

The product of step 3 was used in a reductive amination with 4-oxo-piperidine-1- carboxylic acid tert-butyl ester following the procedure of Example 2 step a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525070B2
Source datasetuspto-grants-2003_02
ORD IDord-849563b5b3e14b7f86ac0c49a90be374
Source noteuspto-grants-2003_02