HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 9958543, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Reactant | HCID 11083914 | HCID 11083914 | — |
| Reactant | HCID 12052585 | HCID 12052585 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 9958543 | HCID 9958543 | 64% |
Reaction Steps
The phenolic indole (4) (50 mg, 0.16 mmole) was dissolved in dichloromethane (2 mL). To the phenol solution was added (S)-allyl lactate (24 mg, 0.19 mmole), triphenylphosphine (50 mg, 0.19 mmole), and diethylazodicarboxylate (DEAD) (0.030 mL, 0.19 mmole) and the reaction was monitored by TLC. Once complete the reaction was purified by silica gel chromatography to give the title compound (44.1 mg, 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525083B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-aac776fa6e974199869b6cc529bdc110 |
| Source note | uspto-grants-2003_02 |