HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 2-formyl-4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carboxylate → 1-[(5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl]methyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 2-formyl-4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carboxylate | HCID 11845085 | — |
| Reactant | 1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride | HCID 22709766 | — |
| Product | 1-[(5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl]methyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine | HCID 22710093 | — |
Reaction Steps
In a similar manner to Referential Example 47 except for the use of 5-tert-butoxycarbonyl-2-formyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525042B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-db1bdf3868aa499b92d629621f710539 |
| Source note | uspto-grants-2003_02 |