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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061029Generated: November 2, 2026

HCID 22709699, compound → 1-[(E)-3-(5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)propenoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine

https://huagongshe.com/reaction/1061029

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22709699HCID 22709699—
Reactant1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochlorideHCID 22709766—
Product1-[(E)-3-(5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)propenoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazineHCID 22709440—

Reaction Steps

In a similar manner to Referential Example 12 except for the use of (E)-3-(5-tert-butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)acrylic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525042B1
Source datasetuspto-grants-2003_02
ORD IDord-673c4ec04fc6478b85b9ba06698c0d09
Source noteuspto-grants-2003_02